| Chemical Specifications | |
|---|---|
| Product Name | Adipotide (FTPP) |
| CAS Number | 859216-15-2 |
| Molecular Formula | C111H206N36O28S2 |
| Molecular Weight | 2557.18 g/mol |
| Purity (HPLC) | ≥ 99.0% |
| Appearance | White Lyophilized Powder |
| Storage | Store at -20°C (Protect from light and moisture) |
What is Adipotide (FTPP)?
Adipotide, scientifically known as Fat-Targeted Proapoptotic Peptide (FTPP), is an extreme, investigational weight-loss compound engineered unlike any other metabolic agent. Available in highly purified 2mg and 5mg vials, it does not rely on appetite suppression or nervous system stimulation. Instead, Adipotide functions as a precision “Hunter-Killer” peptide. It is designed to seek out, bind to, and destroy the specific blood vessels that supply oxygen and nutrients to white adipose tissue, effectively starving and killing fat cells at their source.
Key Features & Research Benefits
Targeted Fat Apoptosis
Induces programmed cell death (apoptosis) exclusively in the microvascular network of white adipose tissue. By cutting off the blood supply, it forces the targeted fat cells to starve, die, and be reabsorbed by the body.
Non-CNS Stimulant
Unlike traditional weight-loss compounds (like amphetamines) that heavily tax the central nervous system, Adipotide works entirely peripherally within the vascular system, eliminating risks of jitteriness, insomnia, or psychological dependency.
Rapid Weight Reduction
In non-human primate research models, Adipotide demonstrated an unprecedented ability to induce an 11% reduction in total body weight and a 39% reduction in fat deposits within just 28 days of administration.
Improves Insulin Resistance
The massive and rapid clearance of metabolically active white adipose tissue (especially visceral fat) directly leads to profound improvements in insulin sensitivity, glycemic control, and overall lipid profiles.
“Hunter-Killer” Precision
Constructed with two distinct domains: a “Homing” domain that acts like a GPS to find the prohibitin protein on fat blood vessels, and a “Killer” domain that triggers mitochondrial disruption and cell death.
Research Grade Purity
Synthesized via advanced solid-phase peptide synthesis (SPPS), ensuring a >99.0% HPLC-verified purity level. This guarantees precise, targeted ablation without off-target toxicity in strict laboratory settings.
How It Works: The “Hunter-Killer” Mechanism
Adipotide (FTPP) is a masterpiece of targeted vascular engineering. To understand its power, you must realize that fat tissue (white adipose tissue) requires a massive, dedicated network of tiny blood vessels (capillaries) to survive and expand. If you destroy the blood vessels, the fat tissue dies. This is the exact mechanism of Adipotide.
The peptide is constructed as a chimeric “Hunter-Killer” molecule consisting of two distinct parts:
1. The “Hunter” (Homing Domain): When introduced into the bloodstream, this specific sequence acts like a guided missile. It ignores healthy tissue and specifically hunts for a protein called prohibitin. Prohibitin is uniquely expressed on the surface of the endothelial cells that line the blood vessels feeding white fat deposits. Once it finds prohibitin, the “Hunter” locks on tightly.
2. The “Killer” (Proapoptotic Domain): Once the molecule has attached itself to the fat-feeding blood vessel, the “Killer” domain penetrates the cell membrane. It travels directly to the mitochondria (the power plants of the cell) and physically disrupts their membranes. This instantly triggers a cellular self-destruct sequence known as apoptosis. The blood vessel cells die, the capillaries collapse, and the blood supply to the fat deposit is completely severed.
Deprived of oxygen and nutrients, the corresponding white fat cells undergo rapid starvation and necrosis. The body’s immune system (macrophages) then safely clears away the dead fat cells, resulting in a permanent, targeted reduction in adipose mass.
🧪 What’s In The Vial
- Active Compound: Adipotide (FTPP)
- State: Sterile, Lyophilized Powder
- Format: Multi-dose Research Vials
- Net Contents: 2mg or 5mg options
- Purity: ≥99.0% (HPLC Verified)
👩🔬 Who Uses It
- Advanced Obesity Researchers
- Vascular Biology Scientists
- Metabolic Syndrome Investigators
- Targeted Apoptosis Laboratories
- Cardiometabolic Trial Administrators
🔗 Best Paired With
- Sterile Bacteriostatic Water (BAC)
- Precision Laboratory Pipettes
- Renal Function Monitoring Tools
- Vial Storage Organizers (-20°C)
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